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用于干细胞研究的小分子化合物

0115278198032651.jpg用于干细胞研究的小分子化合物

 


  Stemgent® 提供一系列独特的小分子--Stemolecules™ ,这类小分子可用于多能干细胞的自我更新和分化的主要信号通路的分析和调节,诱导多能干细胞(iPS)的细胞重编程,诱导和维持干细胞原始状态。

  Stemolecules™为保证高纯度(≥98%)进行了严格检测,通过NMR和质谱进行结构验证,并且测试了对干细胞的细胞毒性。Stemolecules™ 通常用于提高iPS细胞的产生和维持多能干细胞的培养。

 

BrandNameCatalog   NumberSize
Stemolecule™A83-0104-00142 mg
04-0014-1010 mg
Stemolecule™ALK5   Inhibitor (RepSox)04-00151 mg
Stemolecule™All-Trans   Retinoic Acid04-0021100 mg
Stemolecule™BI-D187004-005110 mg
Stemolecule™BIO04-00032 mg
Stemolecule™BIX0129404-00025 mg
Stemolecule™CHIR9902104-00042 mg
04-0004-1010 mg
Stemolecule™CHIR99021 in Solution04-0004-022 mg (10 mM)
Stemolecule™Cyclopamine04-00222 mg
Stemolecule™DAPT04-00415 mg
Stemolecule™Dorsomorphin04-00242 mg
Stemolecule™Doxycycline   hyclate04-001610 mg
Stemolecule™ec23SRP0025 mg
SRP002-22×5mg
Stemolecule™Forskolin04-002510 mg
Stemolecule™GDC-094104-00475 mg
Stemolecule™GSK429286A04-00492 mg
Stemolecule™IDE-204-00272 mg
Stemolecule™KAAD-Cyclopamine04-0028100 μg
Stemolecule™LDN-19318904-00742 mg
04-0074-1010 mg
Stemolecule™LDN-193189   in Solution04-0074-022 mg (10 mM)
Stemolecule™LY41157504-00545 mg
Stemolecule™PD032590104-00062 mg
04-0006-1010 mg
Stemolecule™PD0325901  in Solution04-0006-022 mg (10 mM)
Stemolecule™PD17307404-00082 mg
Stemolecule™Purmorphamine04-00095 mg
Stemolecule™R(+)Bay  K 864404-00135 mg
Stemolecule™RG10804-000110 mg
Stemolecule™SB43154204-00105 mg
04-0010-1010 mg
Stemolecule™SB431542 in Solution04-0010-055 mg (10 mM)
Stemolecule™SB59088504-00802 mg
Stemolecule™SC1 (Pluripotin)04-00111 mg
Stemolecule™SHH Antagonist04-00322 mg
Stemolecule™Sodium Butyrate04-0005500 mg
Stemolecule™Thiazovivin04-00171 mg
Stemolecule™Valproic   Acid04-00075 g
Stemolecule™WH-4-02304-00792 mg
Stemolecule™Wnt   Inhibitor IWP-204-00342 mg
Stemolecule™Wnt   Inhibitor IWP-304-00352 mg
Stemolecule™Wnt   Inhibitor IWP-404-00362 mg
Stemolecule™XAV93904-00462 mg
Stemolecule™Y2763204-00122 mg
04-0012-1010 mg
Stemolecule™Y27632   Dihydrochloride Hydrate04-0012-H-1010 mg
Stemolecule™Y27632 in Solution04-0012-022 mg (10 mM)

 

 

1.

Chen, S., Liu, Z., Lu, S., & Hu, B. (2019). EPEL promotes the migration and invasion of osteosarcoma cells by upregulating ROCK1. Oncology letters, 17(3), 3133-3140.【StemoleculeTM Y-27632】


2.

Zucchini, C., Manara, M. C., Cristalli, C., Carrabotta, M., Greco, S., Pinca, R. S., ... & Gambarotti, M. (2019). ROCK2 deprivation leads to the inhibition of tumor growth and metastatic potential in osteosarcoma cells through the modulation of YAP activity. Journal of Experimental & Clinical Cancer Research, 38(1), 1-14. 【StemoleculeTM Y-27632】


3.

Cong, F., Hao, H., Hsieh, M. H. L., Jiang, X., Liu, J., & Ng, N. (2019). Cancer patient selection for administration of wnt signaling inhibitors using rnf43 mutation status. U.S. Patent Application No. 16/259,419.【StemoleculeTM Wnt Inhibitor IWP-2】


4.

Keller, G., & Craft, A. M. (2019). Keller G, Craft A M. Methods and compositions for generating chondrocyte lineage cells and/or cartilage like tissue. U.S. Patent Application No. 15/977,536. 【StemoleculeTM CHIR99021】


5.

Sun, X., Fu, X., Du, M., & Zhu, M. J. (2018). Ex vivo gut culture for studying differentiation and migration of small intestinal epithelial cells. Open biology, 8(4), 170256.【StemoleculeTM DAPT】


6.

Gieseck III, R. L., Hannan, N. R., Bort, R., Hanley, N. A., Drake, R. A., Cameron, G. W., ... & Vallier, L. (2014). Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture. PloS one, 9(1), e86372.【Stemolecule CHIR99021】


7.

Brick, D. J., Stover, A. E., Nethercott, H. E., Banuelos, M. G., & Schwartz, P. H. (2014). GMP4‐Compatible Production and Expansion of Human Neural Stem Cells. Neural Stem Cell Assays, 35-53. 【StemoleculeTM Y-27632】


8.

Fathi, A., Rasouli, H., Yeganeh, M., Salekdeh, G. H., & Baharvand, H. (2015). Efficient differentiation of human embryonic stem cells toward dopaminergic neurons using recombinant LMX1A factor. Molecular biotechnology, 57(2), 184-194. 【StemoleculeTM SB431542,StemoleculeTM LDN-193189】




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